321839-75-2 crinecerfont

Properti

Penampilan bubuk kuning ke kuning
suhu penyimpanan. 4 derajat, jauh dari kelembaban dan cahaya

Aplikasi:

Crinecerfont (ssr -125543) adalah antagonis reseptor CRF1 yang aktif secara oral yang efektif, terutama digunakan untuk pengobatan hiperplasia adrenal kongenital (CAH). Crinecerfont inhibits pituitary secretion of adrenocorticotropic hormone (ACTH) by blocking the binding of corticotropin releasing factor (CRF) to CRF1 receptors in the pituitary gland, thereby reducing ACTH mediated adrenal androgen production and helping to control androgen levels in adults and children over 4 years old
 

Sinonim:

321839-75-2

Crinecerfont (hidroklorida)

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro{{10} } methylphenyl) ethyl] -5- methyl-n-prop -2- ynyl -1, 3- tiazol -2- amine; hydrochloride

(S) -4- (2- chloro -4- methoxy -5- methylphenyl) -n-(2- cyclopropyl -1- ({{8} } fluoro -4- methylphenyl) ethyl) -5- methyl-n- (prop -2- ynyl) thiazol -2- amina hidroklorida

4- (2- chloro -4- methoxy -5- methylphenyl) -n-[(1s) -2- cyclopropyl -1- ({{{{{{{{{{{{{9} o -4- methylphenyl) ethyl] 5- methyl-n-(2- propynyl) -1, 3- tiazol -2- amina hidroklorida

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