1025967-78-5 Liftegrast

Properti

Penampilan putih hingga pucat padat
Melting point:>163 derajat (Desember)
Titik didih: 811.9 ± 65. 0 derajat
Kepadatan 1.479 ± 0. 06 g/cm3
suhu penyimpanan. Hygroscopic, -20 derajat freezer, di bawah atmosfer inert
kelarutan DMSO (sedikit, dipanaskan, disonikasi), metanol (sedikit, disonikasi)
pKa3.14 ± 0. 10

 

Aplikasi:

Lifitegrast mengurangi agregasi sel darah putih di mata dengan menghalangi interaksi antara LFA -1 dan ICAM -1, dengan demikian mengurangi peradangan mata dan gejala mata kering. Mekanisme ini membuat Lifitegrast memiliki potensi dalam pengobatan penyakit mata kering.

 

Sinonim:

Lifitegrast

1025967-78-5

Xiidra

Sar -1118

(S) -2- (2- (benzofuran -6- carbonyl) -5, 7- Dichloro -1, 2,3, 4- tetra hydroisoquinoline -6- carboxamido) -3- (3- (methylsulfonyl) phenyl) propanoic asam

Shp -606

L-phenylalanine, N-[[2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, { {9}} tetrahydro -6- isoquinolinyl] carbonyl] -3- (methylsulfonyl)-

SAR1118

L-phenylalanine, N-((2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, { {9}} tetrahydro -6- isoquinolinyl) carbonyl) -3- (methylsulfonyl)-

(2S)-2-(((2-(benzofuran-6-ylcarbonyl)-5,7-dichloro-1,2,3,4-tetrah ydroisoquinolin -6- yl) carbonyl) amino) -3- (3- (methylsulfonyl) phenyl) propanooic asam

(2s) -2- [[2- (1- benzofuran -6- carbonyl) -5, 7- dichloro {{7}, {8 {6} {h -1 h-isoquinoline -6- carbonyl] amino] -3- (3- methylsulfonylphenyl) propanoik asam

Lifitegrast

Lifitegrastum

L-phenylalanine, N-[[2- (6- benzofuranylcarbonyl) -5, 7- dichloro -1, 2,3, { {9}} tetrahydro -6- isoquinolinyl] carbonyl] -3- (methylsulfonyl)-; N-[[2- (6- benzofuranylcarbonyl) -5, 7- Dichloro {{18}, 2,3, 4- t etrahydro -6- isoquinolinyl] carbonyl] -3- (methylsulfonyl) -l-phenylalanine; (S)

N-(2- (1- benzofuran -6- carbonyl) -5, 7- Dichloro -1, 2.3, {4- te trahydroisoquinoline -6- carbonyl) -3- (methanesulfonyl) -l-phenylalanine

(S) -2- (2- (benzofuran -6- carbonyl) -5, 7- Dichloro -1, 2,3, 4- tetra hydroisoquinoline -6- carboxamido) -3- (3- (methylsulfonyl) phenyl) propanoic acid; (s) -2- (2- (benzofuran -6- carbonyl) -5, 7- {{17}, 2,3, {{20} {{17}, 2,3, {{{{{16 {20 {{{17 {{{17 {{17 {{{17 {{{17 {{{17 {{{17 {{{17 {{17 { Tetrahydroisoquinoline -6- carboxamido) -3- (3- (methylsulfonyl) phenyl) propanoic asam

(2s) -2- ((((2- (benzofuran -6- ylcarbonyl) -5, 7- {{6 {6}, {{{{{{{{9 {9 {{{9 {{9 {{9 {{9 {{9 {{{9 {{9 {{9 {{{{9 {9 {{{9 {9 {{{{{{{{{{{{{{{{{{{{{{{9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 {9 yl) carbonyl) amino) -3- (3- (methylsulfonyl) fenil) asam propanoat

 

 

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